Some studies do not report back significant improvements in insulin sensitivity have used 50mg daily for 3 months in otherwise healthy overweight aged men with low (less than 1500ng/mL) DHEA; DHEA did not even trend towards significance, and appeared to have no directional effect.  This lack of efficacy resulting in no trend towards significance has been noted elsewhere with doses that should normally work.   In post-menopausal women where DHEA would not show efficacy, the combination of DHEA and mixed exercises did not create efficacy of DHEA. 
As we discussed above, Dianabol carries a strong aromatizing nature, and is a C17-aa anabolic steroid; as such, its side-effects will revolve around these factors. As an aromatizing steroid, this means there can be a testosterone to estrogen conversion, and if estrogen levels go to high it can lead to some complications. When estrogen levels increase, the hormone can attach to the receptors and cause gynecomastia (male-breast enlargement) and it can also promote excess water retention and high blood pressure; Dbol is notorious for promoting high blood pressure. Needless to say, if you already suffer from high blood pressure you should not touch this steroid, but if it's healthy you'll need to ensure it stays this way. For this reason, in-order to combat and avoid these estrogenic side-effects of Dbol, the use of an Aromatase Inhibitor (AI) is often advised. It shouldn't be too hard to see how this can help; after all, an AI inhibits aromatase, but it goes a step further by reducing the body's total estrogen levels. Of course, and this cannot be overstressed, you must keep your doses at a responsible level; most will need at least 20mg per day for any anabolic promotion, with a maximum dosing of 50mg per day. It should be noted; if you've never used this steroid before, you should not start with a high end dose; start low and see how you respond.
Physical examination also provides clues to the nature of immune deficiency. For example, wasting and unexplained weight loss is common in both antibody and cellular immune deficiencies, although any chronic inflammatory condition can be associated with abnormal catabolic states. Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies. Coarse facial features and severe eczema suggest a hyper-IgE syndrome, whereas vitiligo or alopecia areata are associated with mucocutaneous candidiasis with autoimmune polyglandular disease. Hepatosplenomegaly and lymphadenopathy are frequently found in patients with CVID and cellular immune deficiency. Cutaneous fungal infections suggest defects in cellular immunity. Furuncles and soft tissue abscesses are seen in phagocytic disorders. Ocular telangiectasia in association with cerebellar ataxia is the hallmark of ataxia telangiectasia, which leads to progressive combined immunodeficiency. Chronic inflammatory arthritis is seen in antibody and complement deficiencies.