Nasal spray steroids and weight gain

Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen , estrogen , or mineralocorticoid receptors , thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (. mast cell , eosinophil , neutrophil , macrophages , and lymphocytes ) and mediators (. histamine , eicosanoids , leukotrienes , and cytokines ) involved in inflammation . Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability .

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Hi Dr Sharma,
I am a relatively healthy 62 year old. I have suffered with skin rashes face, arms and body ever since a bout of Ross River fever 25 years ago. It seems that whenever I get a bout of Ross River Fever or Glandular fever it comes out through my skin in the form of a red rash that turns dry and itchy after several days. The challenge I am having is that the rash seems to persist now and my skin cycles continuously from red to dry, itchy and scaly to red to dry, itchy and scaly, especially on my arms, wrists, left side of the face and body. I have to continually keep the skin moist with organic chemical free skin lotions but nothing seems to break the cycle. I addition to this and I am not sure if related, I have a very mucousy throat which I cannot expel and continuous throat clearing especially after I sneeze!

Decongestant nasal sprays are available over-the-counter in many countries. They work to very quickly open up nasal passages by constricting blood vessels in the lining of the nose. Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as rhinitis medicamentosa or the rebound effect . Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include:

Nasal spray steroids and weight gain

nasal spray steroids and weight gain

Decongestant nasal sprays are available over-the-counter in many countries. They work to very quickly open up nasal passages by constricting blood vessels in the lining of the nose. Prolonged use of these types of sprays can damage the delicate mucous membranes in the nose. This causes increased inflammation, an effect known as rhinitis medicamentosa or the rebound effect . Decongestant nasal sprays are advised for short-term use only, preferably 5 to 7 days at maximum. Some doctors advise to use them 3 days at maximum. A recent clinical trial has shown that a corticosteroid nasal spray may be useful in reversing this condition. [3] Topical nasal decongestants include:

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