Steroid conversion tables

On the other hand, whenever there is a strong immunologic stimulus (., acute bacterial or viral infection, vaccination, HIV infection), a "false" positive occurs (62, 119). In addition, persons who use injection drugs, have autoimmune or connective tissue diseases (especially systemic lupus erythematosus), or hypergammaglobulinemic states may have "false" positive results. These persons often also have blood tests positive for other factors frequently associated with autoimmune disease such as antinuclear, antithyroid, or antimitochondrial antibodies; rheumatoid factor; and cryoglobulins. A negative specific treponemal test will confirm that the test is a false positive and that syphilis can be excluded.

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The vitamin D endocrine system. In this system, the biologically inactive vitamin D 3 is activated, first in the liver to produce 25-hydroxyvitamin D 3 [25(OH)D 3 ], and the endocrine gland (the kidney) converts it to the hormones 1α,25-dihydroxyvitamin D 3 [1α,25(OH) 2 D 3 ] and 24 R ,25-dihydroxyvitamin D 3 [24 R ,25(OH) 2 D 3 ]. Researchers have identified ≥36 target organs, defined by the presence of the vitamin D receptor (VDR), which is the receptor for the steroid hormone 1α,25(OH) 2 D 3 ; see Table 1 for a list of these target organs. Table 2 lists the 10 extrarenal tissues that investigators have shown possess the 1α-hydroxylase, the enzyme that converts 25(OH)D 3 to the steroid hormone 1α,25(OH) 2 D 3 . Pi, inorganic phosphate.

Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world.  The Merck Manual was first published in 1899 as a service to the community.  The legacy of this great resource continues as the Merck Manual in the US and Canada and the MSD Manual outside of North America.   Learn more about our commitment to Global Medical Knowledge.

Arlan L Rosenbloom, MD  Adjunct Distinguished Service Professor Emeritus of Pediatrics, University of Florida College of Medicine; Fellow of the American Academy of Pediatrics; Fellow of the American College of Epidemiology

Arlan L Rosenbloom, MD is a member of the following medical societies: American Academy of Pediatrics , American College of Epidemiology , American Pediatric Society , Endocrine Society , Pediatric Endocrine Society , Society for Pediatric Research , Florida Chapter of The American Academy of Pediatrics, Florida Pediatric Society , International Society for Pediatric and Adolescent Diabetes

Disclosure: Nothing to disclose.

Steroid conversion tables

steroid conversion tables

Merck & Co., Inc., Kenilworth, NJ, USA is a global healthcare leader working to help the world be well. From developing new therapies that treat and prevent disease to helping people in need, we are committed to improving health and well-being around the world.  The Merck Manual was first published in 1899 as a service to the community.  The legacy of this great resource continues as the Merck Manual in the US and Canada and the MSD Manual outside of North America.   Learn more about our commitment to Global Medical Knowledge.

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