Advair (Fluticasone + Salmeterol) : The original combination inhaler is still the most popular. Basically it combines a steroid with a long acting beta adrenergic (LABA). The steroid controls inflammation while the LABA keeps your lungs relaxed around the clock. The combination of these medicines has worked wonders for many asthmatics. The best part of this medicine is all you need to do is take one puff in the morning and one before bed. This greatly improves complaince, and that alone I think has benefited many asthmatics.
Anyone taking oral steroids or a high dose of inhaled steroids for more than three weeks should be given a steroid treatment card . Small enough to keep in your purse or wallet, this card has room to record the details of your dose and your condition(s). This is so that if you ever need any medical treatment and you're not able to communicate (you're having an asthma attack, for example), the people treating you know you're taking prednisolone and can plan your treatment accordingly. If you are taking oral steroids, or high-dose inhaled steroids, for more than three weeks then you should never suddenly stop them.
Studies with oral and intravenous dosing of radiolabeled ciclesonide have shown an incomplete extent of oral absorption (%). The oral bioavailability of both ciclesonide and the active metabolite is negligible (<% for ciclesonide, <1% for the metabolite). Based on a γ-scintigraphy experiment, lung deposition in healthy subjects is 52%. In line with this figure, the systemic bioavailability for the active metabolite is >50% by using the ciclesonide metered dose inhaler. As the oral bioavailability for the active metabolite is <1%, the swallowed portion of the inhaled ciclesonide does not contribute to systemic absorption.