Depending on the number and character of their functional groups, steroid molecules may show diverse reactivities. Moreover, the reactivity of a functional group varies according to its location within the molecule (for example, esters are formed readily by 3-OH groups but only with difficulty by the 11β-OH group). An important property of steroids is polarity —., their solubility in oxygen-containing solvents (., water and alcohols ) rather than hydrocarbon solvents (., hexane and benzene ). Hydroxyl, ketonic, or ionizable (capable of dissociating to form electrically charged particles) groups in a steroid molecule increase its polarity to an extent that is strongly influenced by the spatial arrangement of the atoms within the molecule.
– Live one day at a time and maximize that day. Focus on doing today’s work to the best of your capability, because that’s all you can do. Don’t think about the gym session tomorrow or the paper you have to hand-in in 2 weeks. Just do what needs to get done today as well as you can.
– Do your tasks in order of importance/urgency.
– If you worry a lot, occupy your day with stimulating work that takes your mind off the worries. In this case, he used two examples: 1) cleaning which is “automated work” is bad if you worry since it doesn’t stimulate you enough and 2) sales in a store where you’re on your feet all day and talking to customers is great since it’s stimulating work that takes your mind off everything else.
– Exercise daily and don’t overeat to keep stress down and stay fit.
– If you feel like you’re overworked and missing out, take out some hours each day to do activities you enjoy. Here he used an example of Rockerfeller who was rich his whole life but never went out and parties or to play and treated his workers like dogs. He was miserable most of the time and nobody liked to be around him. Later on he changed some of these things, but at that time he was already old.
– Give people sincere compliments whenever they deserve it, because that makes them smile and makes your day better. I did this to a young kid in my local grocery store who always gave a good service and cleaned up after me when I broke a lot of stuff because I hit some beer bottles by accident. I told him he gives exceptional service and that he would be a good sales man. He brightened up like I’ve never seen and thanked me like 5 times. Since then we always chat when I shop there.
The early steps in the biosynthesis of steroids of both plants and animals are the same, except that in plants lanosterol is replaced by the related compound cycloartenol, which contains a three-membered ring (C9, C10, C19) in lieu of the nuclear double bond of lanosterol. The side chains of the phytosterols, such as stigmasterol, and of the sterol ergosterol of yeasts and other fungi contain extra carbon atoms that are incorporated in reactions involving S -adenosylmethionine, which donates methyl groups in numerous biological processes. Although most plant tissues contain only traces of cholesterol, this sterol is the biogenetic precursor of such important plant steroids as the sapogenins , glycosides , and alkaloids . Because pregnane derivatives are intermediates in some of these transformations, plants and animals appear to have important features of steroid metabolism in common.