Thyroid hormone and anabolic steroid

About: Thyroid peroxidase (TPO) antibodies, also abbreviated as TPOAb, are antibodies that develop as a result of an autoimmune attack on the thyroid gland. They target the gland, and usually result in destruction of the gland over time. TPOAb antibodies attack thyroid peroxidase, an enzyme that plays a role in the conversion of T4 to T3. Elevated TPOAb levels can be evidence of inflammation of the gland, or tissue destruction such as Hashimoto's disease. Less commonly, TPO are seen in other forms of thyroiditis such as  post-partum thyroiditis .

Thyroid hormones are like heat. When the heat gets back to the thermostat, it turns the thermostat off. As the room cools (the thyroid hormone levels drop), the thermostat turns back on (TSH increases) and the furnace produces more heat (thyroid hormones).

The pituitary gland itself is regulated by another gland, known as the hypothalamus (shown in the picture above in light blue). The hypothalamus is part of the brain and produces TSH Releasing Hormone (TRH) which tells the pituitary gland to stimulate the thyroid gland (release TSH). One might imagine the hypothalamus as the person who regulates the thermostat since it tells the pituitary gland at what level the thyroid should be set.

Thyroid changes can happen during pregnancy. These changes are usually not significant, but some women can develop thyroid disease during pregnancy. Hyperthyroidism occurs in about one in every 500 pregnancies, while hypothyroidism occurs in approximately one in every 250 pregnancies. Hyperthyroidism, and less often, hypothyroidism, may remain after pregnancy. If you develop a thyroid condition during pregnancy, your health care provider will monitor your condition after your baby is born. If you have a history of thyroid disease, be sure to talk with your health care provider if you are pregnant or are thinking of becoming pregnant.

The use of medications and radioactive iodine has made surgery for hyperthyroidism much less common. Surgery involves removing diseased parts of the thyroid gland through an open incision in the neck. Complications of thyroid surgery may include damage to the nerves that supply the vocal cords, infection, and damage to the parathyroid glands (four tiny glands in the thyroid tissue that regulate calcium levels in the body). If a total thyroidectomy is performed all of the thyroid tissue is removed and the patient will need to be maintained on thyroid replacement therapy for the rest of their life.

Thyroid hormone and anabolic steroid

thyroid hormone and anabolic steroid

The use of medications and radioactive iodine has made surgery for hyperthyroidism much less common. Surgery involves removing diseased parts of the thyroid gland through an open incision in the neck. Complications of thyroid surgery may include damage to the nerves that supply the vocal cords, infection, and damage to the parathyroid glands (four tiny glands in the thyroid tissue that regulate calcium levels in the body). If a total thyroidectomy is performed all of the thyroid tissue is removed and the patient will need to be maintained on thyroid replacement therapy for the rest of their life.

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