Comparative Biosciences Inc., a premier veterinary preclinical contract research organization, is committed to providing expert high-quality contract research services to the veterinary and animal health industry. Extensive experience industry provides our staff with a solid track record in preclinical veterinary research and drug development capabilities. We work closely with both sponsors and Veterinary Clinical Research Organizations to support studies that are needed to support regulatory submissions to the USDA and FDA. We offer toxicology, pharmacokinetic and pharmacology studies in all relevant veterinary species (juvenile and adult) such as dogs, cats, minipigs, pigs, and also mice, rats, hamsters, guinea pigs, chinchillas, ferrets, gerbils, and rabbits, limited studies with small ruminants and horses are also possible. We offer a wide range of routes of administration as well as unusual and specialized routes of administration for a wide variety of test articles including small molecules, large molecules, biologics (vaccines, antibodies, proteins, toxins, viral, stem cells, radiolabeled products), and other related test articles and devices.
In many countries, the local nomenclature for a vet is a protected term, meaning that people without the prerequisite qualifications and/or registration are not able to use the title, and in many cases, the activities that may be undertaken by a vet (such as animal treatment or surgery) are restricted only to those people who are registered as vet. For instance, in the United Kingdom, as in other jurisdictions, animal treatment may only be performed by registered vets (with a few designated exceptions, such as paraveterinary workers ), and it is illegal for any person who is not registered to call themselves a vet or perform any treatment.
The human–animal bond has evolved and diversi?ed down the ages. Dogs, cats and even horses, have long ful?lled the role of faithful companion and indeed, as exempli?ed by the introduction of seeing and hearing dogs, there may be a critical level of co-dependency between the species. In the twenty-?rst century, the animal types that are kept as pets in many parts of the world are extensive ranging from reptiles through rodents to ruminants and beyond. As would be predicted by the nature of the relationship, the approach to treatment of a companion animal is often closely aligned to that which would have been offered to their owner. However, an increasing awareness of welfare issues, such as the recognition that animals expe- ence pain and the proven bene?ts of disease prevention in intensive farming units, together with the growth in zoos and wildlife parks, has increased the likelihood of food producing and non-domesticated animals receiving medicinal products during their life-time. Although many of the individual drugs or classes of drugs administered to animals are the same as, or derived from, those given to man, the safe and effective use of drugs in animals often cannot be achieved by simply transposing knowledge of drug action on, or behaviour in, the body from one species to another. The impact of the anatomical, physiological and pathophysiological variability that spans the animal kingdom can often profoundly alter drug response.