With so much attention on PEDs, especially in baseball with the Mitchell Report and multiple congressional hearings, it appears that the black market is going to be the one with the most to gain. Individuals who decide to use these substances will not have many alternatives, especially with these once over-the-counter precursors being banned.
Throughout the history of anabolic steroids, a lot has been learned on what these drugs can and cannot do. There is still a place for them in the medical community and – in some people’s minds – athletics, as well. The obvious is sometimes ignored – that even the thought of using PEDs should not occur until one is an adult.
That is the one common denominator in both the opponents and proponents of steroids. Both camps can do themselves a little justice by becoming more educated on the subject.
Stanozolol appears to offer less hepatic stress than an equivalent dose of Dianabol (methandrostenolone). Studies giving 12mg of stanozolol per day for 27 weeks failed to demonstrate clinically-significant changes in markers of liver function, including serum aspartate amino-transferase, alanine amino-transferase, gamma-glutamyltransferase, bilirubin, and alkaline phosphatase. 621 Relative hepatotoxicity increases as the dosage escalates, so hepatic dysfunction should still be a concern. In rare instances, high doses (alone or in combination with other steroids) have been implicated in cases of serious life-threatening hepatotoxicity in bodybuilders. Injectable stanozolol has also been implicated in severe hepatotoxicity in an otherwise healthy bodybuilder, 622 and should not be used as an alternative medication when liver toxicity precludes oral stanozolol use.
Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .